In line with its mission to improve the quality of life for persons who may benefit from the rehabilitation practice of prosthetic, orthotic, mobility and assistive technology, ISPO facilitates knowledge exchange, promotes research and evidence-based practice, and fosters international collaboration and consensus through publications.

Further to its scientific journal Prosthetics and Orthotics International (POI) that is published six times per year, ISPO compiles reports and other resources on an ad-hoc basis.